Publications

Publications

Holloway JN, Murthy S, El-Ashry D.  A cytoplasmic substrate of mitogen-activated protein kinase is responsible for estrogen receptor-alpha down-regulation in breast cancer cells: the role of nuclear factor-kappaB. Mol Endocrinol. 2004 Jun;18(6):1396-410.

Oh AS, Lorant LA, Holloway JN, Miller DL, Kern FG, El-Ashry D. Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells. Mol Endocrinol. 2001 Aug;15(8):1344-59.

Abstracts

Murthy, S, Holloway, JN, El-Ashry, D.   Identification of MAP kinase substrates responsible for the downregulation of ERa in breast cancer cells.  94th Annual Meeting of the American Association of Cancer Research, Washington, DC, 2003, Abstract #1953.

Holloway, JN, Alexander, J, and El-Ashry D.  A substrate of MAPK is Responbsible for the Downregulation of ERa in Breast Cancer Cells.  93rd Annual Meeting of the American Association for Cancer Research, San Francisco, CA, 2002. Abstract #5332.

Extramural Grant

2001-2004 (PI)

Downstream Signaling Mechanism Underlying MAPK-Induced Generation of the ER-Negative Phenotype

DAMD17-01-1-0247 

Direct Costs: $66,000